HMG CoA Reductase Inhibitors
Pharmacogenomic Evidence*
Two SLCO1B1 variants, rs4149056 and rs4363657, have been shown to be associated with increased risk of statin-induced myopathy [PMID: 18650507].
Related PharmGKB Resources
| Drug information: | HMG CoA Reductase Inhibitors |
|---|---|
| Variants of PGx interest: | SLCO1B1(rs4149056), SLCO1B1(rs4363657) |
| Very Important Pharmacogene (VIP) pages: | SLCO1B1 VIP |
| Allele frequency information: | SLCO1B1(rs4149056), SLCO1B1(rs4363657) |
| Gene pages: | SLCO1B1 |
| Gene Variants pages: | SLCO1B1 variants |
| Pathways: | Statin Pathway |
| Datasets: | Not available |
| Genetics information: | All variant annotations mentioning HMG CoA Reductase Inhibitors |
| Literature: | Publications related to statin and SLCO1B1 PGx |
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