Quinidine

Pharmacogenomic Information in the Context of the FDA-Approved Drug Label*

Quinidine is a Class I antiarrhythmic medication which inhibits CYP2D6.

Excerpt from the quinidine drug label:

"Quinidine is not metabolized by cytochrome P450IID6, but therapeutic serum levels of quinidine inhibit the action of cytochrome P450IID6, effectively converting extensive metabolizers into poor metabolizers. Caution must be exercised whenever quinidine is prescribed together with drugs metabolized by cytochrome P450IID6."

(For the complete drug label text with sections containing pharmacogenetic information highlighted, see the Quinidine drug label PDF.)