Gene:
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2

PharmGKB contains no dosing guidelines for this gene. To report known dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB contains no drug labels with pharmacogenomic information for this gene. To report a drug label with PGx, click here.

PharmGKB contains no clinical annotations for this gene. To report clinical variants, click here.

PharmGKB contains no genetic tests for this gene. To report genetic tests, click here.

The table below contains information about pharmacogenomic variants on PharmGKB. Please follow the link in the "Variant" column for more information about a particular variant. Each link in the "Variant" column leads to the corresponding PharmGKB Variant Page. The Variant Page contains summary data, including PharmGKB manually curated information about variant-drug pairs based on individual PubMed publications. The PMIDs for these PubMed publications can be found on the Variant Page.

The tags in the first column of the table indicate what type of information can be found on the corresponding Variant Page.

Links in the "Drugs" column lead to PharmGKB Drug Pages.

Variant?
(build 132)
Alternate Names ? Drugs ? Alleles ?
(+ chr strand)
Function ? Amino Acid?
Translation
VIP No Clinical Annotations available No Variant Annotations available
rs890293 CYP2J2*7, CYP2J2:G-50T, CYP2J2:G-76T, g.30364412C>A, g.4930G>T C/A Not Available
Alleles, Functions, and Amino Acid Translations are all sourced from dbSNP build 132

Overview

Alternate Names:  CYPIIJ2; Cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase),; OTTHUMP00000010550; arachidonic acid epoxygenase; cytochrome P450 2J2; cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2; flavoprotein-linked monooxygenase; microsomal monooxygenase
Alternate Symbols:  CPJ2
PharmGKB Accession Id: PA27112

Details

Cytogenetic Location: chr1 : p32.1 - p32.1
GP mRNA Boundary: chr1 : 60358980 - 60392423
GP Gene Boundary: chr1 : 60355980 - 60402423
Strand: minus
Product Name: No data available
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

PharmGKB contains no curated pathways for this gene. If you would like to volunteer to work on a pathway, please let us know.

External Pathways

Links to non-PharmGKB pathways.

  1. eicosanoid metabolism - (BioCarta via Pathway Interaction Database)
  2. Fatty acids - (Reactome via Pathway Interaction Database)

Curated Information ?

Gene Relationship Evidence
PPARA
  •   
  •   
Publications

Curated Information ?

Drug Class Relationship Evidence
Antihistamines For Systemic Use
  •   
  •   
Publications
xenobiotics
  • PD
  • PK
Publications

Non-Curated Information ?

A list of non-curated publications that mention this gene along with other drugs is available.

Curated Information ?

Disease Relationship Evidence
Asthma
  •   
  •   
Variants
Brain Ischemia
  •   
  •   
Variants
Cardiovascular Diseases
  •   
  •   
Publications
Coronary Artery Disease
  •   
  •   
Variants
Coronary Disease
  •   
  •   
Variants
Coronary Stenosis
  •   
  •   
Variants
Drug Toxicity
  • PD
  • PK
Publications
Essential hypertension
  •   
  •   
Variants
Hypertension
  •   
  •   
Variants
Myocardial Infarction
  •   
  •   
Publications, Variants
Neoplasms
  • PD
  • PK
Publications
nephrotoxicity
  • PD
  • PK
Publications
Parkinson Disease
  • PD
  • PK
Publications
Stomach Neoplasms
  •   
  •   
Publications
Stroke
  •   
  •   
Publications

LinkOuts

Entrez Gene:
1573
OMIM:
601258
UCSC Genome Browser:
NM_000775
RefSeq RNA:
NM_000775
RefSeq Protein:
NP_000766
RefSeq DNA:
AC_000044
AC_000133
NC_000001
NG_007931
NT_032977
NW_001838579
NW_921351
MutDB:
CYP2J2
ALFRED:
LO007920S
LO031629V
HuGE:
CYP2J2
Comparative Toxicogenomics Database:
1573
ModBase:
P51589
HumanCyc Gene:
HS05902
HGNC:
2634

Common Searches

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