PharmGKB Mission Statement

Our Mission: To collect, encode, and disseminate knowledge about the impact of human genetic variations on drug response. We curate primary genotype and phenotype data, annotate gene variants and gene-drug-disease relationships via literature review, and summarize important PGx genes and drug pathways.

The knowledge base offers information as a research tool and will:

• Collect and disseminate knowledge about the impact of human genetic variation on drug responses
• Curate and display primary genotype and phenotype data
• Annotate gene variants and gene-drug-disease relationships via literature reviews
• Summarize important pharmacogenomic genes and drug pathways
• Enable consortia examining important questions in pharmacogenomics