PGRN Mission Statement

Vision: To lead discovery and advance translation in genomics, in order to enable safer and more effective drug therapies

Major indicators of success:

• Discovery of novel insights into mechanisms relating genomic variation to differences in drug responses
• Demonstration of the use and utility of genomic information to improve outcomes for drug therapies
• Incorporation of genomic data to predict and personalize medicine use into routine clinical practice

Mission of the PGRN:
PGRN investigators, individually and collectively, will:

• Implement studies in basic, translational, and clinical science to advance the scientific vision
• Develop novel experimental methods and tools to solve pharmacogenomic problems
• Share data and, where feasible, biological samples in collaborations
• Foster cross-disciplinary teams for discovery and dissemination of new information
• Build effective partnerships and alliances with key stakeholders outside the PGRN
• Engage related disciplines to advance the application of pharmacogenomic knowledge
• Work together to make the network become more than the sum of the parts

Mission of PharmGKB:
The knowledge base offers information as a research tool and will:

• Collect and disseminate knowledge about the impact of human genetic variation on drug responses
• Curate and display primary genotype and phenotype data
• Annotate gene variants and gene-drug-disease relationships via literature reviews
• Summarize important pharmacogenomic genes and drug pathways
• Enable consortia examining important questions in pharmacogenomics