VIP Annotations
The Very Important Pharmacogenes, or VIP project, is an initiative to provide annotated information about Genes, Variants, Haplotypes and Splice Variants of particular relevance for Pharmacogenetics and Pharmacogenomics (PGx).
| VIP Gene | Gene Name |
|---|---|
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| ACE | angiotensin I converting enzyme |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| ADH1B | alcohol dehydrogenase IB (class I), beta polypeptide |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide |
| ADRB1 | adrenergic, beta-1-, receptor |
| ADRB2 | adrenergic, beta-2-, receptor, surface |
| AHR | aryl hydrocarbon receptor |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| BRCA1 | breast cancer 1, early onset |
| COMT | catechol-O-methyltransferase |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP2C19 | cytochrome P450, family 2, subfamily C, polypeptide 19 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DPYD | dihydropyrimidine dehydrogenase |
| DRD2 | dopamine receptor D2 |
| F5 | coagulation factor V |
| GSTP1 | glutathione S-transferase pi |
| HMGCR | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase |
| KCNJ11 | potassium inwardly-rectifying channel, subfamily J, member 11 |
| MTHFR | 5,10-methylenetetrahydrofolate reductase (NADPH) |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| P2RY12 | purinergic receptor P2Y, G-protein coupled, 12 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| SCN5A | sodium channel, voltage-gated, type V, alpha (long QT syndrome 3) |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TPMT | thiopurine S-methyltransferase |
| TYMS | thymidylate synthetase |
| UGT1A1 | UDP glucuronosyltransferase 1 family, polypeptide A1 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 |